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Glucose modulates the interferon response in WT islets. Islets from AdarWT mice were cultured for 3 days in 5 or 11 mM glucose and treated for 24 h with 800 u/mL IFNα, with or without 4 μM ruxolitinib. Each dot represents RNA expression levels from 30 islets isolated from AdarKO mice (n 5). ISG expression was assayed by RT-qPCR and normalized to Actb expression. n 6.
#Bar Plot#Error Bars#Scatter Plot#Glucose#Interferon Response#WT Islets#AdarWT Mice#Islets#IFNα#Ruxolitinib#RNA Expression#ISG Expression#RT-qPCR
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