Bar Plot from Scientific Research

Quantification of average MafA, proinsulin, and insulin staining levels in GFP-positive beta cells from 5 to 6 independent experiments shows significant reduction in MafA and proinsulin levels, but not in insulin levels, in AdarKO compared with AdarHET cells and in untreated versus ruxolitinib treated AdarKO GFP-positive beta cells.*p < 0.05,***p < 0.001,****p < 0.0001; ns, non-significant; Students two-tailed t test; error bars indicate mean SEM.

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