Top: schema of the action potential (AP) firing pattern of SFO TMEM63B neurons from Tmem63b Cre/+ (left) mice and Tmem63b Cre/Cre mice (right) before and after hypertonic stimulation. Bottom: AP are clipped for clarity. Black dashed lines show membrane potential; membrane potential was obtained from voltage histograms (blue gaussian curve). Threshold (blue dashed lines), AP threshold, was determined at the point where the voltage trace reached 10 mV/ms.
