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Comparison of the performance of GATK HaplotypeCaller (gray), variation graph (vg) (blue), HAPI with uniform prior (yellow), and HAPI with informed prior (orange) in calling CCR5delta32 on 144 ancient simulated genomes. Performance is shown as MCC, using the simulated genomes called by each method across different coverages (0.3x10x) and across all three deletion genotypes (RR, RD, and DD).
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