Illustration from Scientific Research

Haplotype A consists of CCR5delta32 and 86 tag variants, including two SNPs with an r2value of 1 (rs113341849 and rs113010081, green), two SNPs with an r2value of 0.9027 (rs79815064 and rs1157443, pink), and 82 variants with an r2value of 0.8602 (gray). All r2values are related to the CEU population (Table S1A). The haplotype is located on chr3 3p21.31, spans > 0,19 Mb, and encompasses several genes: CCR3, CCR2, CCR5, and CCRL2. Detailed information on the genomic locations of the genes, CCR5delta32, and the 86 tag variants are provided in Figure S1B.

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