Illustration from Scientific Research

Schematics showing a human tumor-T cell pair designated for this study. A375-A2-ESO-FG, human A375 melanoma cell line engineered to express the tumor antigen NY-ESO-1, its matching MHC molecule (HLA-A2), and a dual-reporter comprising a firefly luciferase and an enhanced green fluorescence protein (FG). ESO-T, human CD8 T cell engineered to express an NY-ESO-1 antigen-specific TCR. ESOp, NY-ESO-1 peptide.

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