Bar Plot from Scientific Research

LDL-cholesterol levels in mouse serum, measured with an LDL-cholesterol assay kit 168 h after starting the rupintrivir dosing (left) and relative LDL-cholesterol reduction compared to wild-type mice (right). Relative decrease was calculated by dividing the average LDL-cholesterol levels of experimental groups by the average LDL-cholesterol level of the wild-type group. In panels g, h , data are shown as mean ± SD, with individual data points ( n = 5–6 mice per group). Statistical significance was calculated by means of Welch’s two-tailed t -test, * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001, ns, not significant.

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