Line Plot from Scientific Research

Stability diagrams of cell adhesion complexes in the case of MEF WT cells obtained by projecting the bistability regions shown in a and b onto the horizontal plane. The black, red and blue solid curves mark the onset of the cusp catastrophe and bifurcations due to saddle-node points moving to infinity, which lead to the formation of biphase–monophase boundaries (green dotted curves), which affect the shapes of cell traction curves both within and beyond the bistability region. The insets around the bistability region illustrate representative cell traction curves within each domain. The graphs show that the elasticity of the intracellular part of molecular clutches and the myosin II density have a profound effect on the mechanosensitive behaviour of cell adhesion.

DOI