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Motor skills assessed by FT IOI Mean showed significant improvements at week 26 ( P =0.025; n = 112 (placebo) and n = 95 (pridopidine)), week 65 ( P =0.016; n = 104 (placebo) and n = 91 (pridopidine)) and week 78 ( P = 0.028; n = 71 (placebo) and n = 69 (pridopidine)). All replicates represent independent participants. Statistical analyses were performed using a MMRM with two-sided nominal P values. The unit of analysis was the individual participant. Data are presented as LSMean, with error bars indicating 95% CI. * P < 0.05, ** P < 0.01.

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