Scatter Plot from Scientific Research

Difference in median promoter methylation for genes when amplified versus when not amplified (y axis). A value greater than 0.2 indicates increased DNA methylation when amplified. The x axis indicates the ratio of gene expression between amplified versus non-amplified regions. Positive values indicate gene expression scales with CN amplification. Genes highlighted yellow are potentially under DNA-methylation-dependent dosage compensation, as their methylation, but not their expression, scales with CN. Genes with expression levels that scale with CN but do not scale with DNA methylation are highlighted red.

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