Plasma mAb levels measured at a subclinical infection, at viral blip, at the dominant virus infection and at acute viremia (VL = 1,000 copies per millilitre), for animals in group 2 or 3 where appropriate (n = 6 animals per group total). In each graph, the fold increase in the median mAb concentration relative to the ITS103.01 or ITS102.03 IC 80 (marked by a dotted line for reference) is indicated above the data points. Individual animal data points are coloured by treatment group. Open circles represent secondary subclinical infections or viral blips for a given animal. The overlaid boxes and middle line indicate the IQR and median, respectively, and the whiskers indicate the range (Extended Data Fig. 3).