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When 4-hydroxybutyric acid is input as a target structure into BioPKS pipeline, the top PKS design from RetroTide synthesizes 4-hydroxybutyric acid completely in just two modules. Hydroxymalonyl-CoA is recommended as a starter unit while malonyl-CoA is recommended as an extender unit. Since any additional post-PKS modifications are not required, BioPKS pipeline terminates.
#Workflow#Flowchart#Illustration#Network#BioPKS pipeline#PKS design#RetroTide#4-hydroxybutyric acid#Hydroxymalonyl-CoA#Malonyl-CoA#Starter unit#Extender unit
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