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ChIP-seq of H3K27ac (first two tracks) and H3K27me3 (two last tracks) show an accumulation of H3K27ac at the Pitx1 locus (black arrows) in proximal Prx1-Cre;Eed flox/- ( Eed -/- ) compared to wildtype (WT) forelimbs and an overall reduction of H3K27me3 signal.
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