Median longitudinal plasma mAb levels (error bars indicate range; n = 6 animals for ITS01, n = 18 for ITS06.02, n = 12 for ITS103.01) with respect to the day of first viral challenge. For animal G4-3, the longitudinal plasma mAb levels for this animal were excluded from the median as high endogenous reactivity to the ITS01 anti-idiotypic antibody prevented calculation of the mAb decay curve (Extended Data Fig. 1 ).
