Protein Structure from Scientific Research

Putative mechanism of AcrIIC1 interaction with the Cas9 HNH domain. The primary structure is the NmeHNH-AcrIIC1 complex (PDB id: 8IF0), with the pink region representing the AcrIIC1 identified in this study. AcrIIC1 was fitted to the complex using ChimeraX’s Matchmaker function. Source data are provided as a Source Data file.

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