Plasma ITS103.01 levels measured at the time of the likely challenge causing a viral blip, at the time of the viral blip, at the challenge that probably led to infection and at the time of acute viremia (VL equal to 1,000 copies per millilitre). In each graph, the fold increase of the median mAb concentration relative to the ITS103.01 IC 80 (marked by a dotted line for reference) is indicated above the data points (Extended Data Figs. 1 and 2 and Supplementary Table 1 ). In e, data points for individual animals are shown and coloured according to treatment group ( n = 6 animals per group in total). The overlaid boxes and middle line indicate the interquartile range (IQR) and median, respectively, and the whiskers indicate the range.