Rate of viremia increase (upslope) measured from synchronized VL curves when VL was equal to 1,000 copies per millilitre. Animals in the antibody treatment group were pooled according to whether they received the fully neutralizing ITS103.01 or the partially neutralizing mAbs. Group 1 (control) animals are shown separately. For each graph, groups were compared by two-tailed one-way analysis of variance, and all pairwise comparisons were assessed using Tukeys honest significant difference (HSD) test; significant (adjusted P < 0.05) differences are indicated. In b, data points for individual animals are shown and coloured according to treatment group ( n = 6 animals per group in total). The overlaid boxes and middle line indicate the interquartile range (IQR) and median, respectively, and the whiskers indicate the range.