Dot plot highlighting the differences between the Reactome pathways (q < 0.05 and FC >=1) obtained by one-sided GSEA in men and women in stage F4 compared with controls. setSIZE indicates the total number of genes present in each specific gene set. P.adjust indicates the Benjamini and Hochberg adjusted P values. GeneRatio is k / n , where k is the overlap between the genes of interest and the gene set and n is the number of all unique genes of interest. CAM, cell adhesion molecule; ECM, extracellular matrix; HCM, hypertrophic cardiomyopathy; JAK, Janus kinase; MAPK, mitogen-activated protein kinase; STAT, signal transducer and activator of transcription.
