Microscopy from Scientific Research

Representative surface-rendered images of Iba1 + microglia and engulfed Homer-GFP in the dorsal striatum of 4-month-old zQ175 Homer-GFP mice and WT Homer-GFP littermates. Scale bar, 10 m. Bar charts show quantification of the relative % microglia engulfment of Homer-GFP in 4-month-old zQ175 Homer-GFP mice relative to that seen in WT Homer-GFP littermate controls, n = 5 WT Homer-GFP and 5 zQ175 Homer-GFP mice. Unpaired two-tailed t -test, P = 0.036.

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