Representative case showing the potential disconnect between assessment of LN involvement on radiology and pathology. Top left, the pretreatment CT scan showed an enlarged LN. Bottom left, the CT scan just before surgical resection demonstrated an approximately 50% reduction in the size of the LN. Right, photomicrograph of the same LN in the definitive resection specimen showed an MPR (90% reduction in tumor), highlighting the underestimation of pathologic response by imaging. The regression bed is surrounded by a white dotted line and is shown on higher power in top right. RVT is shown in the lower right and is marked by yellow asterisks.
