Illustration from Scientific Research

The AAA GWAS loci for which we have identified a candidate causal gene are depicted along with the plausible relationship to its underlying biological mechanism. Loci names are based on the candidate causal gene identified in our analysis. However, the biological pathway(s) remain unclear for many associated loci and, as such, the resultant annotation may prove incorrect in some cases. Gene names are colored according to the gene prioritization scheme used to obtain the candidate (red, protein-altering variants; blue, consensus of indicators and green, nearest gene).

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