Axes show MO (x axis; n case/control = 11,718/1,330,747) and VD (y axis; n case/control = 30,297/86,134). log(OR) is calculated for the effect allele. The effects of variants that have been colored and annotated with gene names differ between the migraine subtypes at a significance threshold of 0.0012 = 0.05/43. The 95% CIs for the log(ORs) are shown for annotated variants. Effects are adjusted with sample overlap (r ij ) estimated from counts of cases, controls and the counts of overlaps in these groups between phenotypes 70 from all cohorts except FinnGen (for which we only have summary statistics). The parameter representing sample overlap between MO and MA is r ij = 0.023 and MO and VD is r ij = 0.012. Dashed lines show the coordinate axes, the diagonal and a line through the origin with slope = 1 (Methods; see Supplementary Tables 13 and 14 and Supplementary Fig. 4 for VD versus MA plot).
