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Schematic of eQTL integration analysis, aiming to test whether trans -regulatory relationships learned from Perturb-seq are also present in eQTL studies. For all gene pairs in which gene i exerts an effect on gene j (that is, has a significant KD effect in our Perturb-seq screen), we would expect that gene i and gene j are enriched for cis -by- trans eQTLs.

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