Heatmap from Scientific Research

Heat maps of perturbation effect sizes (inferred with FR-Perturb) from the KO (left) and KD (right) screens. Rows: top 50 perturbed genes based on the average magnitude of effects on all downstream genes. Columns: top 2,000 downstream genes based on the average magnitude of effects of all perturbed genes acting on them. Rows and columns are clustered using Leiden clustering. Clusters are labeled based on their GO enrichment terms. All effects with q > 0.2 are whited out.

DOI