HD diameter was observed to increase two and three times with lower pH of 5 and 3, respectively, for QD-INS coated with 100 µg ml –1 CS/GS. C57BL/6 mice pre-treated with QD-INS (20 IU kg –1 ) coated with increasing polymer concentrations demonstrated reduced fasting BG only at 100 µg ml –1 CS/GS concentration