Microscopy from Scientific Research

Cortical tissue response. Left: representative brain section, postimplantation (left hemisphere) immunohistochemically stained for Iba-1. White arrow indicates the area of interest that was set at 3,000 m from midline, based on average centre of device implantation. Red box: 8 magnification area used for microglial phenotype morphological analysis. Yellow box: 20 magnification area used to take representative images for the Iba-1 analysis in Supplementary Fig. 14 . Right: EGNITE device implant location shown by the red line on coronal and sagittal rat brain sections.

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