Protein Structure from Scientific Research

Five classes of translating 80S ribosomes bound to different cofactors. Class 1 and 2 are in pre-translocational state with rotating 40S. L1 stalk is colored yellow, eEF2 is colored green. Class 3, 4 and 5 are in the post-translocational state with non-rotating 40S. eEF1A is colored magenta, A/T-tRNA is colored red, P-site tRNA is colored blue and E-site tRNA is colored green. Section views show the different cofactors inside the inter-subunit cavities.

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