Bar Plot from Scientific Research

IL1B gene activation using the indicated dCas12a fusion proteins when targeted to each corresponding promoter using a pool of 2 crRNAs (for IL1B). All samples were processed for qPCR at 72 h post-transfection in HEK293T cells. See the source data for more information. Data are the result of 4 biological replicates. Data are presented as mean ± s.e.m. P values were determined using unpaired two-sided t -test. NLS, nuclear localization signal.

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