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e, f show the interactive effect of the human modification index (HM) and latitude on MPD (two-sided Student’s t-test: t-value = -3.29, P = 0.001). The lines represent the model predictions when fixing HM at its 10%, 50% and 90% quantiles. All relationships are statistically significant (P < 0.001), and all R2 values have been adjusted.
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