Workflow from Scientific Research

A flow chart of the K18-hACE2 mice infected with the SARS-CoV-2 Delta strain experiment. K18-hACE2 mice were divided into 5 groups: vehicle (infected control, blue circle, n = 10), nirmatrelvir 200 mg/kg plus ritonavir (RTV) 50 mg/kg (infected, red square, n = 10), simnotrelvir 200 mg/kg plus ritonavir 50 mg/kg (infected, green triangle, n = 10), simnotrelvir 50 mg/kg plus ritonavir 50 mg/kg (infected, purple inversed triangle, n = 10), and mock infection (uninfected control, orange diamond, n = 2).

DOI