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Thermodynamic measurements of compounds 2 and 7, nirmatrelvir, and simnotrelvir binding to SARS-CoV-2 3CL pro. The thermodynamic profiles are shown as histograms with the Gibbs free energy of binding (G; light blue), enthalpy (H; salmon) and entropy ( T S; light orange). The data are plotted as the mean SD from three independent experiments.
#Bar Plot#Clustered#Error Bars#Thermodynamic measurements#Compound 2#Compound 7#Nirmatrelvir#Simnotrelvir#SARS-CoV-2 3CLpro#Gibbs free energy#Enthalpy#Entropy
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