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Model of synthetic lethality between PELO dependency and 9p21.3 / and MSI-H cancers. Created in Lucid ( lucid.co ). Data are mean s.e.m. of biological replicates: n = 3 for (b d). Significance was calculated using right-tailed Students t -test in b . Representative data from one experiment are shown. All experiments were performed twice, except for experiments in c , d , f , which were performed once. For immunoblots, -tubulin and vinculin were used as loading controls.

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