Bar Plot from Scientific Research

The half maximal activation voltage shift (ΔV 1/2 ) of WT KCNQ2 and mutants by 10 μM CBD. Data are presented as mean ± SEM. An unpaired two-tailed t test was performed to compare WT and each mutant. ** p = 0.0036 for F104A, * p = 0.0307 for W236A, ** p = 0.0083 for L272A, and p = 0.3123 for T296A. For W236A, n = 3 individual cells; For WT and other mutants, n = 5 individual cells.

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