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Peripheral blood was collected from healthy individuals prior to vaccination and following prime and boost immunization with Ad26.COV2.S ( n = 20), BNT162b2 ( n = 8), and mRNA-1273 ( n = 5) for transcriptomic profiling using bulk RNA sequencing. Samples were collected from two TTS patients on days 15, 16, and 19 following Ad26.COV2.S vaccination and from healthy individuals following prime and boost immunization with Ad26.COV2.S ( n = 20), BNT162b2 ( n = 5), and mRNA-1273 (6) for proteomics profiling using the SomaScan platform. Created with BioRender.com.

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