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Open access visualization of Illustration, HKU1-A Spike, Carbohydrate Receptor, S1 A Domain, S1 B Domain
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The HKU1-A spike engages a primary carbohydrate receptor, containing a 9-O-acetylated 2,8-linked disialoside, through the S1 A domain. This causes the allosteric opening of the neighbouring S1 B domain, which then binds to a putative secondary receptor. Created with BioRender.com.

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