Rates of screen-detected (SC) and interval cancer (IC) per 1,000 non-initial screening examinations with 95% confidence intervals between 2010 and 2016. The red line depicts the rates of screen-detected breast cancer as reported by the Cooperative Association (CA) of the German MSP based on data for all non-initial MSP participants [ 10 , 11 , 12 , 13 , 14 , 15 , 16 ]. Of note, these rates are not age-standardized. To facilitate comparison, we therefore also show the non-standardized rates for claims data, in addition to the age-standardized rates (using the old standard population of Europe as reference). Rates of interval cancers are also shown stratified by the year of diagnosis (first vs. second year after screening attendance).