Microscopy from Scientific Research

Selected plane in bladder centre with tumour; light-sheet excitation from right. Tumour (Tu) detectable with a dashed yellow line delineating its surface exposed to the bladder inner cavity. Healthy tissue defined with a dark lamina propria (Lp) and a bright layer of urothelium (Ut), surrounded by detrusor muscles (Dm). Delineating tumour against inner tissues is more challenging; the tumour’s limits could lie anywhere within the orange dashed area (Supplementary Video 3 ). n = 1. ‘Glow’ colour scale: sLS showing nanobots (inside bladder) and agarose crystals (outside).

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