Left: tumour volumes (determined by MRI) on days 7 and 14 after cell implantation for the different study groups (n = 6 per group, biological replicates). Results are expressed in a box plot (centre line at the median; upper and lower bounds at 75th and 25th percentiles, respectively; one dot per animal) with whiskers at minimum and maximum values. Right: 2D DW-MRI images of the bladder (hypointense circular region) of two representative mice at t = 7 and 14 days after inoculation of MB49 cells. Scale bars, 2 mm. 3D renders of whole bladders (transparent) and tumours (purple) are presented next to each MRI image.