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Coiled-coil conformation of the wild type and p.(R433_Q435del) sequences at residues 403–463 as predicted by DeepCoil2. The coiled-coil domain may be affected by the loss of residues 433–435 in the altered protein. The propensity of coiled-coil conformation and detected peaks are indicated in blue and light blue for the wild-type sequence and in red and pink for the mutated sequence
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