Pathway from Scientific Research

Probabilistic causal network and key driver analysis results for the NK cell-mediated cytotoxicity module. This PBMC transcriptome module was significantly enriched with PBMC asthma genes. The arrow indicates the overall causality flow with key drivers at the top level. Level indicates path length of the gene from a key driver. Genes on higher levels have greater causal impact on downstream genes. Color, shade, and shape indicate key driver, module membership, and PBMC asthma genes as summarized in the legend. Selected non-key drivers are additionally labeled, as they are recognized to function with the upstream key drivers.

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