Scatter Plot from Scientific Research

The progression of cerebral organoid development is illustrated (upper). Representative bright-field images showing the progression of cerebral organoids derived from healthy control (CTRL) and patient ( OXR1 Ex18 ) iPSC clones (lower left). Black arrows point the expanding neuroepithelial formation in CTRL clones from day 8 and the poorly developed neuroepithelia buds observed in the OXR1 Ex18 cerebral organoids at day 15. The body size of cerebral organoids (lower right) is quantified by summing the products of bi- dimensional measurements (SPD). SPD=Longest diameter (LD) longest diameter perpendicular to the LD. n = 15–20 organoids of each clone, * p < 0.05.

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