Manhattan plots for genes Klrb1 with over-dominant trans-eQTL mapping to Tbx21. Within each Manhattan plot, the eQTL is marked by a dotted rectangular frame, with the same color as the peak SNP dot (blue—additive; sky blue—partial-dominant; purple—complete-dominant; red—over-dominant), and all linked SNPs with -log10( P ) > 0.5 are colored likewise. The regional Manhattan plots of the peak signal of each eQTL and the scatter plots of two cis-eQTLs are also shown as insets. The pairs of scatter plots to the right of each Manhattan plot compare the expression of each gene with Tbx21 (nearby additive cis-eQTL), showing how these nearby genes are correlated with independent sets of trans-eQTLs. Each dot represents one animal, color-coded by the genotype of the peak SNP