Line Plot from Scientific Research

Data from panel A converted into derivative form (i.e., enzyme rate vs time) to measure the rate of inhibitor-induced changes to the enzyme rate (rate of change of rate) and the extent of inhibition at different inhibitor concentrations. Note: experiments at 2 and 10 uM Ivosidenib showed roughly the same rate of inhibition as 5 and 20 uM but were omitted for clarity.

DOI