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Mechanistic understanding of the polyanion influences. A. KD values of the different polyanions with the peptide and anhydride model as obtained from ITC analysis. KD,1 was obtained with AcF(RG)3N-NH2, and KD,2 with AcF(RG)3D-OH. Right: Example titration obtained from titrating AcF(RG)3N-NH2 to PVS38. The CCC values for the peptide anhydride and the anhydride model are in good agreement.
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