Chimerism levels in indicated hematopoietic cell subsets relative to the donor (young)- or host (aged)-derived HSCs in aged recipients ( left , n = 10). Young recipients were used for comparison ( right , n = 4). p value for each comparison is presented. Gray, red, and blue circles represent young donor, aged host, and young host groups, respectively. In ( b–d ), error bars denote mean ± SEM. Statistical significance was determined by unpaired two-sided t test with Welch correction in ( b–c ) and ( e ), one-way ANOVA with a Tukey test in ( d ), two-sided Wilcoxon matched-pairs signed rank test in ( g ) and paired two-sided t test in ( i ). Source data are provided as a Source Data file.
