Quantification of HCR fluorescence signals for indicated genes across each condition around the wound area (local) and across the body (systemic). The number of polyps showing a similar expression pattern as depicted in the panel over the total number of imaged polyps: for MMP17, n= 14/16 intact polyps, n= 10/13 physa-amputated polyps, n= 19/20 mid-body-amputated polyps; for MMP3i, n= 13/15 intact polyps, n= 13/14 physa-amputated polyps, n= 20/21 mid-body-amputated polyps; and for ADAMTS6, n= 14/17 intact polyps, n= 14/16 physa-amputated polyps, n= 14/17 mid-body-amputated polyps (see Table S4). Data are presented as mean ± SD. Each dot represents a measurement from one polyp. All statistical tests presented: unpaired Student’s two-tailed t test: p< 0.0001: ∗∗∗∗; p< 0.001: ∗∗∗; p< 0.01: ∗∗; p<0.05: ∗; n.s., not significant. See also Figure S5 and Table S4.
