Representative images of muscle tissue stained with H&E with quantification of the myofibre cross-sectional area. Scale bars for H&E, 200 m. For each group, H&E images were counted from n = 4 mice: n = 3,287 myofibres for vehicle-treated mdx (median, 1,200.087 m 2 ; 25th percentile, 1,200.08 m 2 ; 75th percentile, 2,420.57 m 2 ), n = 4,553 myofibres (median, 1,144.176 m 2 ; 25th percentile, 639.52 m 2 ; 75th percentile, 2,013.52 m 2 ) for non-magnetic NT-MAG-Exo myo III; n = 3,294 myofibres (median, 1,947.214 m 2 ; 25th percentile, 1,260.30 m 2 ; 75% percentile, 2,682.62 m 2 ) for NT-MAG-Exo myo III. Violin plots showing CSA median (dotted lines) and quartiles (solid lines); Kruskal Wallis with Dunn’s multiple-comparison test.
