Summary data showing changes in [cAMP] i in astrocytes in response to ZM241385, ATP or ATP in the presence of ZM241385, recorded in hippocampal slices. In the box-and-whisker plots, the central dot indicates the mean, the central line indicates the median, the box limits indicate the upper and lower quartiles, and the whiskers extend to 1.5 the interquartile range from the quartiles. In panels b – d , traces show averaged (mean s.e.m.) recordings from several individual cells in a representative experiment. In panels b , e , f , the numbers in parentheses indicate the number of individual cells/number of separate slices or cultures prepared from the same number of animals. P values were determined by one-way analysis of variance (ANOVA) followed by Sidaks post-hoc test.